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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD3
All Species:
19.7
Human Site:
S274
Identified Species:
36.11
UniProt:
Q12873
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12873
NP_001005271.2
2000
226592
S274
G
H
K
R
R
S
K
S
P
R
V
P
D
G
R
Chimpanzee
Pan troglodytes
XP_512012
1846
210165
S273
G
H
K
R
R
S
K
S
P
R
V
P
D
G
R
Rhesus Macaque
Macaca mulatta
XP_001111066
1981
224269
S274
G
H
K
R
R
S
K
S
P
R
V
P
D
G
R
Dog
Lupus familis
XP_536627
1977
223828
S252
G
H
K
R
R
S
K
S
P
R
V
P
D
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PDQ2
1915
217732
P281
P
D
A
K
K
P
K
P
K
K
V
A
P
L
K
Rat
Rattus norvegicus
Q9JIX5
2581
290674
T288
Q
G
E
S
K
R
I
T
L
V
L
Q
Q
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q06A37
3011
338194
T338
M
N
Q
N
L
G
L
T
N
N
T
P
M
N
Q
Frog
Xenopus laevis
NP_001080504
1893
214670
V266
N
A
R
K
K
P
K
V
V
R
P
P
E
T
K
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
L403
A
V
P
L
K
L
L
L
Q
P
Q
S
N
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
S266
G
K
K
G
R
R
P
S
G
K
V
P
T
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
A233
E
E
A
R
I
N
R
A
A
A
K
V
D
K
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
Y32
A
A
A
H
Q
Q
N
Y
F
N
D
S
D
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.3
97.8
97.3
N.A.
67.6
22.6
N.A.
N.A.
23.4
66
22.7
N.A.
55
N.A.
47.2
N.A.
Protein Similarity:
100
90.5
98.1
98
N.A.
78.3
37.6
N.A.
N.A.
37.2
77.1
38.5
N.A.
68.6
N.A.
61.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
0
N.A.
N.A.
6.6
20
0
N.A.
40
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
33.3
N.A.
N.A.
33.3
53.3
13.3
N.A.
53.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.6
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
24
0
0
0
0
8
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
47
8
0
% D
% Glu:
8
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
39
8
0
8
0
8
0
0
8
0
0
0
0
31
0
% G
% His:
0
31
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
39
16
31
0
47
0
8
16
8
0
0
8
24
% K
% Leu:
0
0
0
8
8
8
16
8
8
0
8
0
0
16
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
8
0
8
8
0
8
16
0
0
8
8
0
% N
% Pro:
8
0
8
0
0
16
8
8
31
8
8
54
8
8
0
% P
% Gln:
8
0
8
0
8
8
0
0
8
0
8
8
8
0
16
% Q
% Arg:
0
0
8
39
39
16
8
0
0
39
0
0
0
0
39
% R
% Ser:
0
0
0
8
0
31
0
39
0
0
0
16
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
0
8
0
8
16
0
% T
% Val:
0
8
0
0
0
0
0
8
8
8
47
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _